Control of time-dependent biological processes by temporally patterned input.

@article{Brezina1997ControlOT,
  title={Control of time-dependent biological processes by temporally patterned input.},
  author={Vladimir Brezina and Irina V Orekhova and Klaudiusz R. Weiss},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 19},
  pages={10444-9}
}
Temporal patterning of biological variables, in the form of oscillations and rhythms on many time scales, is ubiquitous. Altering the temporal pattern of an input variable greatly affects the output of many biological processes. We develop here a conceptual framework for a quantitative understanding of such pattern dependence, focusing particularly on nonlinear, saturable, time-dependent processes that abound in biophysics, biochemistry, and physiology. We show theoretically that pattern… CONTINUE READING

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