Control of thrombotic thrombocytopenic purpura by sirolimus in a child with juvenile myelomonocytic leukemia and somatic N-RAS mutation.

Abstract

We describe an infant who developed juvenile myelomonocytic leukemia (JMML) at the age of 6 months. Myeloproliferation was effectively controlled by low-dose cytosine arabinoside and 13-cis retinoic acid therapy. Two years after therapy for JMML was stopped, at the age of 5 years, the patient developed autoimmune thrombotic thrombocytopenic purpura (TTP… (More)
DOI: 10.1002/pbc.25013

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Cite this paper

@article{Maschan2014ControlOT, title={Control of thrombotic thrombocytopenic purpura by sirolimus in a child with juvenile myelomonocytic leukemia and somatic N-RAS mutation.}, author={Michael Maschan and Vlasta O Bobrynina and Lili Khachatryan and Irina Kalinina and Galina G Solopova and Pavel V Avdonin and Tatiana V. Nasedkina and Galina A Novichkova and Alexei A Maschan}, journal={Pediatric blood & cancer}, year={2014}, volume={61 10}, pages={1871-3} }