Control of the superior colliculus by the lateral prefrontal cortex.

  title={Control of the superior colliculus by the lateral prefrontal cortex.},
  author={Stefan Everling and Kevin D. Johnston},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  volume={368 1628},
Several decades of patient, functional imaging and neurophysiological studies have supported a model in which the lateral prefrontal cortex (PFC) acts to suppress unwanted saccades by inhibiting activity in the oculomotor system. However, recent results from combined PFC deactivation and neural recordings of the superior colliculus in monkeys demonstrate that the primary influence of the PFC on the oculomotor system is excitatory, and stands in direct contradiction to the inhibitory model of… CONTINUE READING
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