Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium.

@article{Harrison1975ControlOT,
  title={Control of the malignant hyperpyrexic syndrome in MHS swine by dantrolene sodium.},
  author={Gail Grigsby Harrison},
  journal={British journal of anaesthesia},
  year={1975},
  volume={47 1},
  pages={
          62-5
        }
}
  • Gail Grigsby Harrison
  • Published in
    British journal of…
    1975
  • Medicine
  • Experiments are described which demonstrate that dantrolene sodium effectively terminates the syndrome of malignant hyperpyrexia induced in susceptible swine by exposure to halothane. Dantrolene is also shown to block initiation of the syndrome of malignant hyperpyrexia by halothane in MHS swine. Therapeutic use of this drug in patients with anaesthetic-induced malignant hyperpyrexia appears to be indicated. 

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 70 CITATIONS, ESTIMATED 41% COVERAGE

    Ryanodinopathies: RyR-Linked Muscle Diseases.

    VIEW 1 EXCERPT
    CITES BACKGROUND
    HIGHLY INFLUENCED

    The cytoprotective effects of dantrolene: a ryanodine receptor antagonist.

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Maligne Hyperthermie

    VIEW 3 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    Mind the magnesium, in dantrolene suppression of malignant hyperthermia.

    • Stephen C Cannon
    • Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 2017

    FILTER CITATIONS BY YEAR

    1976
    2018

    CITATION STATISTICS

    • 4 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-8 OF 8 REFERENCES

    Dantrolene sodium in the treatment of spasticity.

    VIEW 1 EXCERPT

    Dantrolene, a direct acting skeletal muscle relaxant.

    VIEW 1 EXCERPT

    Clinical pharmacophysiology of dantrolene sodium

    • N. Mayer, S. A. Newcombe
    • Br. J. Anaesth.,
    • 1972

    Biochemical changes associated with malignant hyperpyrexia induced by halothane in susceptible pigs

    • Berman, G.G.M. C Harrison, A. B. Bull, J. E. Kench
    • Nature (Land.),
    • 1970
    VIEW 1 EXCERPT

    Recent advances in an understanding of malignant hyperpyrexia

    • S. J. Saunders, J. F. Biebuyck, +3 authors J. Terblanche
    • 1969