Control of the immune system by oxysterols and cancer development.

  title={Control of the immune system by oxysterols and cancer development.},
  author={Catia Traversari and Vincenzo Russo},
  journal={Current opinion in pharmacology},
  volume={12 6},
Oxysterols/oxysterol receptors have been shown to modulate several immune cell subsets, such as macrophages, T-cells and B-cells, neutrophils and dendritic cells (DCs). They participate in the control of several pathologic processes, that is, infectious diseases, atherosclerosis and autoimmunity. Moreover, some oxysterols have also been shown to favor tumor progression by dampening the antitumor immune response. The cellular responses generated by oxysterols depend on the engagement of Liver X… CONTINUE READING
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