Control of the T follicular helper-germinal center B-cell axis by CD8⁺ regulatory T cells limits atherosclerosis and tertiary lymphoid organ development.

Abstract

BACKGROUND The atheromodulating activity of B cells during the development of atherosclerosis is well documented, but the mechanisms by which these cells are regulated have not been investigated. METHODS AND RESULTS Here, we analyzed the contribution of Qa-1-restricted CD8(+) regulatory T cells to the control of the T follicular helper-germinal center B… (More)
DOI: 10.1161/CIRCULATIONAHA.114.010988

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@article{Clment2015ControlOT, title={Control of the T follicular helper-germinal center B-cell axis by CD8⁺ regulatory T cells limits atherosclerosis and tertiary lymphoid organ development.}, author={Marc Cl{\'e}ment and Kevin Guedj and Francesco Andreata and Marion Morvan and Laetitia Bey and Jamila Khallou-Laschet and Anh-Thu Gaston and Sandrine Delbosc and J M Alsac and Patrick Bruneval and Catherine Deschildre and Marie Le Borgne and Yves Castier and Hye-Jung Kim and Harvey Cantor and Jean-Baptiste Michel and Giuseppina Caligiuri and Antonino Nicoletti}, journal={Circulation}, year={2015}, volume={131 6}, pages={560-70} }