Control of the Bacterial Cell Cycle by Cytoplasmic Growth

@article{Koch2002ControlOT,
  title={Control of the Bacterial Cell Cycle by Cytoplasmic Growth},
  author={A. L. Koch},
  journal={Critical Reviews in Microbiology},
  year={2002},
  volume={28},
  pages={61 - 77}
}
  • A. L. Koch
  • Published 2002
  • Biology, Medicine
  • Critical Reviews in Microbiology
For free-living single-celled organisms, it can be assumed that it is their success in acquiring resources and converting them into cytoplasm that controls the timing of their cell cycles. Cytoplasm is the sink for the bulk of the environmental resources. It must be the case that this type of control must operate in dilute cultures under adequate nutrition in a constant environment. It follows that there ought to be mechanisms that measure or count the cell's biomass or some component of the… Expand
Theoretical models for the regulation of DNA replication in fast-growing bacteria
Growing in always changing environments, Escherichia coli cells are challenged by the task to coordinate growth and division. In particular, adaption of their growth program to the surrounding mediumExpand
Single-cell model of prokaryotic cell cycle.
TLDR
Universal equations were derived for different cell parameters depending on constructivist cell cycle parameters (unit mass, replication and division times, cell age, cell cycle duration) based on selected growth laws of cell mass (linear, exponential). Expand
GROWTH RATE DEPENDENT CARBON CATABOLITE REPRESSION (CCR) IS DETERMINED BY MOLECULAR CROWDING (MC) IN E. COLI CELLS
TLDR
Macromolecular crowding in the cell represents the root cause of both CCR and the “OxPhos to glycolysis” switch evolved to ensure optimal cell metabolism. Expand
Effect of the Min System on Timing of Cell Division in Escherichia coli
TLDR
The results indicate that the Min system affects the septum formation rate, and in the absence of the Min proteins this rate is reduced, leading to the observed strongly randomized cell division events and the longer division waiting times. Expand
Cell cycle synchronization of Cupriavidus necator by continuous phasing measured via flow cytometry.
TLDR
The results show that the time required for a complete cell cycle of Cupriavidus necator JMP 134 is independent of the chosen phasing cycle duration, provided that each process cycle lasts at least 3 h which is much longer than the time needed for a single DNA replication cycle. Expand
Mathematical Model of a Cell Size Checkpoint
TLDR
A mechanism linking cell size and cell cycle, involving the downstream action of Cdr2 on Wee1 phosphorylation, is proposed, and is modeled using a deterministic reaction-diffusion-convection system interacting with a Deterministic model describing microtubule dynamics. Expand
Concentration and Assembly of the Division Ring Proteins FtsZ, FtsA, and ZipA during the Escherichia coli Cell Cycle
TLDR
The concentration of the cell division proteins FtsZ, FtsA, and ZipA and their assembly into a division ring during the Escherichia coli B/r K cell cycle have been measured in synchronous cultures obtained by the membrane elution technique and revealed no organized structure in newly born cells. Expand
Fundamental principles in bacterial physiology-history, recent progress, and the future with focus on cell size control: a review.
TLDR
This article presents a comprehensive overview of major ideas and approaches developed since the early 20th century in bacterial physiology and explains how the pioneering work from the first golden era has influenced various rediscoveries of general quantitative principles and significant further development in modern bacterial physiology. Expand
Whole-cell modeling framework in which biochemical dynamics impact aspects of cellular geometry.
TLDR
A mathematical framework for modeling biological cells from a physicochemical perspective allows the modeling of complex cellular behaviors, including self-replication, and is illustrated by constructing two self- Replication whole-cell models. Expand
THE ROLE OF PHYSICAL AND GEOMETRICAL FACTORS IN THE GROWTH OF LIVING ORGANISMS
TLDR
This paper considers overgrowth from the physical perspective, introduces the notion of a growth ratio as an important geometrical characteristic of the growth and overgrowth processes, and generalizes the findings. Expand
...
1
2
...

References

SHOWING 1-10 OF 69 REFERENCES
What is the bacterial growth law during the division cycle?
  • S. Cooper
  • Medicine, Biology
  • Journal of bacteriology
  • 1988
TLDR
The introduction of the static analysis of cell growth by Collins and Richmond (4) marked a new approach to the study of bacterial growth, which indicates that there is a continuously increasing rate of synthesis during the division cycle. Expand
Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins.
TLDR
A development of a new approach to the analysis of Escherichia coli replication control shows direct evidence that SeqA is a bona fide negative regulator of replication initiation, and implications for the complex interplay amongst growth, cell division, and DNA replication are discussed. Expand
Attachment of the chromosome to the cell poles: the strategy for the growth of bacteria in two and three dimensions.
TLDR
A new extension of the concept that polar sites bind specifically origin and terminus DNA of the chromosome is presented that can explain how division takes place in one and then in another dimension to form two-dimensional tablets of four cells or large planar arrays. Expand
Characterization of cell-cycle-specific events in synchronous cultures of Escherichia coli: a theoretical evaluation.
TLDR
A model was constructed of a synchronous culture of Escherichia coli cells as would be derived from a growing population immobilized on a surface, and applied to the case of one stable and one unstable cellular component, indicating that the presence of cycle-specific events may be easily detectable, but their timing and duration are very difficult to establish in synchronous growth experiments. Expand
The regulation of cell size and the control of mitosis.
TLDR
Four general classes of model are presented' which agree with general criteria arc established to which any model must conform which describes the regulation of cell size and mitosis and are argued that several published models are inconsistent. Expand
Autorepressor model for control of DNA replication.
TLDR
A simple feedback control system, the elements of which exist in bacteria, might answer the problem of how the rate of cell division in Escherichia coli is determined by the frequency of initiation of chromosome replication. Expand
Regulation of the eukaryotic cell cycle: molecular antagonism, hysteresis, and irreversible transitions.
TLDR
A simple model of the antagonistic interactions between cyclin-dependent kinases and the anaphase promoting complex is presented, which shows how progress through the cell cycle can be thought of as irreversible transitions between two stable states of the regulatory system. Expand
The initiation mess?
TLDR
This review concerns the mechanisms which control initiation of chromosome replication in enterobacteria with respect to cell growth and discusses the role of DnaA protein accumulating to a threshold level in this process. Expand
The initiation mass for DNA replication in Escherichia coli K‐12 is dependent on growth rate.
TLDR
The initiation mass of E. coli K‐12 cells is found to increase monotonically with decreasing growth rate, indicating that the control for timing of initiation is not governed by a direct connection between mass accumulation and the molecule(s) determining initiation of replication. Expand
Initiation of DNA replication in bacteria: analysis of an autorepressor control model.
TLDR
A detailed quantitative analysis, using computer simulation, of the control model first put forward schematically by Sompayrac & Maaløe in 1973, in which a single operon codes for both the initiator protein and an autorepressor is presented. Expand
...
1
2
3
4
5
...