Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum.

@article{Takeuchi2005ControlOS,
  title={Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum.},
  author={Tomonori Takeuchi and Taisuke Miyazaki and Masahiko Watanabe and Hisashi Mori and Kenji Sakimura and Masayoshi Mishina},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2005},
  volume={25 8},
  pages={2146-56}
}
Precise topological matching of presynaptic and postsynaptic specializations is essential for efficient synaptic transmission. Furthermore, synaptic connections are subjected to rearrangements throughout life. Here we examined the role of glutamate receptor (GluR) delta2 in the adult brain by inducible and cerebellar Purkinje cell (PC)-specific gene targeting under the pure C57BL/6 genetic background. Concomitant with the decrease of postsynaptic GluRdelta2 proteins, presynaptic active zones… CONTINUE READING