Control of spatial patterning and cell-type proportioning in Dictyostelium.

  title={Control of spatial patterning and cell-type proportioning in Dictyostelium.},
  author={Samarendra K. Mohanty and Richard A. Firtel},
  journal={Seminars in cell & developmental biology},
  volume={10 6},
The spatial patterning of prestalk and prespore cells in the slug arises from the differential sorting of newly differentiated cell types as the mound forms. This pattern is highly organized along an anterior-posterior axis and is constant irrespective of the size of the organism. Cell-type differentiation is plastic until late in development. A change in the ratio of cell types resulting from removal of part of the slug leads to a rapid restoration of the original ratio of the cell types… CONTINUE READING

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