Control of smooth muscle development by the myocardin family of transcriptional coactivators.

@article{Wang2004ControlOS,
  title={Control of smooth muscle development by the myocardin family of transcriptional coactivators.},
  author={Da-zhi Wang and Eric N Olson},
  journal={Current opinion in genetics & development},
  year={2004},
  volume={14 5},
  pages={558-66}
}
Differentiation of smooth muscle cells (SMCs) is accompanied by the transcriptional activation of an array of muscle-specific genes that confer the unique contractile and physiologic properties of this muscle cell type. The majority of smooth muscle genes are controlled by serum response factor (SRF), a widely expressed transcription factor that also regulates genes involved in cell proliferation. Myocardin and myocardin-related transcription factors (MRTFs) interact with SRF and potently… CONTINUE READING

4 Figures & Tables

Connections & Topics

Mentioned Connections BETA
Differentiation of smooth muscle cells ( SMCs ) is accompanied by the transcriptional activation of an array of muscle - specific genes that confer the unique contractile and physiologic properties of this muscle cell type .
Differentiation of smooth muscle cells ( SMCs ) is accompanied by the transcriptional activation of an array of muscle - specific genes that confer the unique contractile and physiologic properties of this muscle cell type .
Differentiation of smooth muscle cells ( SMCs ) is accompanied by the transcriptional activation of an array of muscle - specific genes that confer the unique contractile and physiologic properties of this muscle cell type .
Differentiation of smooth muscle cells ( SMCs ) is accompanied by the transcriptional activation of an array of muscle - specific genes that confer the unique contractile and physiologic properties of this muscle cell type .
All Topics