Control of renal function by intrarenal angiotensin II in the dog.

@article{Levens1990ControlOR,
  title={Control of renal function by intrarenal angiotensin II in the dog.},
  author={N R Levens},
  journal={Journal of cardiovascular pharmacology},
  year={1990},
  volume={16 Suppl 4},
  pages={S65-9}
}
  • N R Levens
  • Published 1990 in Journal of cardiovascular pharmacology
The purpose of this study was to determine if conversion of angiotensin I to angiotensin II (Ang II) within the kidney is important in the control of renal function following sodium depletion. Infusion of a short-acting angiotensin I-converting enzyme (ACE) inhibitor, BPP5a, into the left kidney at a dose of 30 micrograms/kg/min failed to alter significantly the pressor response to Ang I administered in a femoral vein. Mean arterial pressure and renal function in the contralateral noninfused… CONTINUE READING