Control of pyrimidine biosynthesis in Escherichia coli by a feed-back mechanism.

@article{Pardee1956ControlOP,
  title={Control of pyrimidine biosynthesis in Escherichia coli by a feed-back mechanism.},
  author={Arthur B. Pardee and Rebecca Yates},
  journal={The Journal of biological chemistry},
  year={1956},
  volume={221 2},
  pages={
          757-70
        }
}
The mechanisms by which a cell can control its biosynthetic processes are important from the point of cellular economy, yet they are little understood. It is known that bacteria must have such control systems, since their biochemical processes are so well coordinated, as shown by failure of the cell to accumulate large amounts of metabolites in the medium (1). Several indications of control mechanisms have been found. One type of observation is that addition of a few micrograms per ml. of… CONTINUE READING

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at D aa-F aber C acer Initute, on S etem er 26, 2012 w w w .jb.org D ow nladed fom

H. F. Umbarger
Science, 123, • 1956
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