Control of oocyte growth and meiotic maturation in Caenorhabditis elegans.

@article{Kim2013ControlOO,
  title={Control of oocyte growth and meiotic maturation in Caenorhabditis elegans.},
  author={Seongseop Kim and Caroline A. Spike and David Greenstein},
  journal={Advances in experimental medicine and biology},
  year={2013},
  volume={757},
  pages={277-320}
}
In sexually reproducing animals, oocytes arrest at diplotene or diakinesis and resume meiosis (meiotic maturation) in response to hormones. Chromosome segregation errors in female meiosis I are the leading cause of human birth defects, and age-related changes in the hormonal environment of the ovary are a suggested cause. Caenorhabditis elegans is emerging as a genetic paradigm for studying hormonal control of meiotic maturation. The meiotic maturation processes in C. elegans and mammals share… CONTINUE READING

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