Control of nerve cell formation from multipotent stem cells in Hydra.

@article{Berking1979ControlON,
  title={Control of nerve cell formation from multipotent stem cells in Hydra.},
  author={Stefan Berking},
  journal={Journal of cell science},
  year={1979},
  volume={40},
  pages={193-205}
}
Feeding of starved animals provides a very short signal which determines stem cells to differentiate into nerve cells after the next mitosis. Only those stem cells become determined which are just in the middle of their S-phase at the time of feeding. Stem cells of any other stage of the cycle do not become determined. Nerve cell determination is suppressed by very low concentrations of an endogenous inhibitor. The inhibitor exerts its effect only during the first half of the S-phase, not… CONTINUE READING

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