Control of nasal obstruction in perennial allergic rhinitis

  title={Control of nasal obstruction in perennial allergic rhinitis},
  author={De Yun Wang and Md Tanveer Raza and Bruce R. Gordon},
  journal={Current Opinion in Allergy and Clinical Immunology},
Purpose of reviewNasal obstruction, the cardinal symptom of persistent (perennial) allergic rhinitis, is one of the most common symptoms encountered in primary care and in specialist clinics. It is difficult to quantify by clinical examination, and, hence, objective assessment of the nasal airway is critical to rhinologic research. Nasal obstruction in persistent allergic rhinitis must be treated the year round, and therefore treatment choices, costs, and compliance all become important public… 

Prevalance of upper airway symptoms and aspects on treatment of nasal polyposis

Self-reported non-allergic rhinitis symptoms are highly prevalent independent of age, and reduced sense of smell is a common complaint.

Pathophysiology of nasal congestion

Mucosal inflammation underlies many of the specific and interrelated factors that contribute to nasal congestion, as well as other symptoms of both allergic rhinitis and rhinosinusitis.

Extranasal symptoms of allergic rhinitis are difficult to treat and affect quality of life.

Pathophysiology of nasal obstruction and meta‐analysis of early and late effects of levocetirizine

It is demonstrated convincingly that levocetirizine shows a consistent effect on nasal obstruction as early as over the first 2 h and sustained over 6 weeks, as well as over a longer period of time.

Pregnancy rhinitis : Pathophysiological effects of oestrogen and treatment with oral decongestants

In the human nasal mucosa of healthy subjects, immunocytochemistry showed distinct oestrogen receptor (ER) s positive cells in all sections, which indicate that Oestrogen may play a role in the development of pregnancy rhinitis.

Nasal Obstruction

Various medical therapies and surgical techniques will be described for the treatment of nasal obstruction, the primary symptom of persistent allergic rhinitis (AR).

Intranasal steroids or radiofrequency turbinoplasty in persistent allergic rhinitis: effects on quality of life and objective parameters

Nasal congestion refractory to antihistamine appears to be improved by INS at some point, while reduced significantly by RFT in objective and subjective parameters, which might be a safe and effective treatment of option in AR compared with INS.

Surgical treatment for allergic rhinitis

Standard surgical treatment for allergic rhinitis has not been established, but a variety of surgery for patients who do not respond to appropriate medication can help relieve allergic symptoms and these effective but invasive procedures should be chosen carefully.

Maxillary Sinus Aeration in Allergic Rhinitis

Total maxillary sinus volumes were found to be significantly smaller for patients with a positive SPT compared to patients with the suspicion of allergic rhinitis, indicating that AR has a negative impact on maxillarysinus aeration.



Use of intranasal cromolyn sodium for allergic rhinitis.

Intranasal cromolyn has an excellent safety record, is available as an over-the-counter medication, and has been proved to be efficacious in patients with allergic rhinitis, which is associated with impaired occupational function and performance in school and decreased quality of life.

Effect of submucosal diathermy in chronic nasal obstruction due to turbinate enlargement.

Submucosal diathermy is carried out under local anesthesia and is a safe, effective procedure for improving nasal breathing in patients with chronic obstructive inferior turbinates, both on a short-term and long-term basis.

Rhinitis in pregnancy.

In pregnancy, the safety profile of drugs is the primary item to be considered and it is recommended to use "older drugs" because more data about their safety are available.

Laser Surgery of the Inferior Turbinate for Allergic Rhinitis with Seasonal Exacerbation: An Acoustic Rhinometry Study

It is concluded that laser surgery can be successfully applied to patients whose allergies show seasonal exacerbation by airborne pollen.

The efficacy of nasal surgery among patients with and without allergies.

The allergic status of the patient is not an effective predictive criterion for the outcome of nasal surgery in patients with perennial nasal obstruction and the efficacy of this procedure is rather low and better preoperative criteria are required to improve its efficacy.

Assessment of early- and late-phase nasal obstruction in atopic patients after nasal allergen challenge.

In order to study the types of nasal obstruction in allergic rhinitis, nasal allergen challenge was performed in 18 atopic patients, compared with a control group consisting of 10 healthy volunteers.

Desloratadine: an update of its efficacy in the management of allergic disorders.

Although comparative studies with second-generation and other recently developed H(1)-antihistamines are needed to define the drug's clinical profile more clearly, desloratadine can be expected to claim a prominent place in the management of allergic disorders in general, and in the amelioration of specific symptoms of allergy in patients with such disorders.

Argon plasma coagulation for intractable nasal obstruction occurring in patients with allergic rhinitis.

New surgical treatment for the intractable nasal obstruction in patients with nasal allergy by using Argon Plasma Coagulator (APC) was introduced, and it was found that nasal obstruction was ameliorated in all cases, though a crust and fibrin membrane adhered to the mucosa between 2 to 4 weeks after surgery, resulting in temporary exacerbation of nasal obstruction.

Definition, prevalence and development of nasal obstruction

Nasal obstruction is defined as discomfort manifested as a feeling of insufficient airflow through the nose, a subjective complaint that is one of the complaints of patients with atrophic rhinitis, a disorder with wide nasal cavities.