Control of nanobiointerfaces generated from well-defined biomimetic polymer brushes for protein and cell manipulations.

@article{Iwata2004ControlON,
  title={Control of nanobiointerfaces generated from well-defined biomimetic polymer brushes for protein and cell manipulations.},
  author={Ryoko Iwata and Piyawan Suk-In and Vipavee P Hoven and Atsushi Takahara and Kazunari Akiyoshi and Yasuhiko Iwasaki},
  journal={Biomacromolecules},
  year={2004},
  volume={5 6},
  pages={2308-14}
}
To better understand protein/material and cell/material interactions at the submolecular level, well-defined polymer brushes consisting of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) on silicon wafers were prepared by atom transfer radical polymerization (ATRP). Silicon wafers were treated with 3-(2-bromoisobutyryl)propyl dimethylchlorosilane (BDCS) to form a monolayer that acts as initiators for ATRP. Silicon-supported BDCS monolayers were soaked in a methanol/water mixture solution… CONTINUE READING

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