Control of mucoglycoprotein output from the rabbit nose.

  title={Control of mucoglycoprotein output from the rabbit nose.},
  author={Jennifer M. Pell and R J Phipps and U M Wells and John G Widdicombe},
  journal={The Journal of physiology},
A method for the collection of rabbit nasal washings to analyse outputs of mucous glycoproteins is described. The radiolabels sodium [35S]sulphate and [3H]glucose are bound to the glycoproteins. The release of bound 35S and 3H was enhanced by cervical sympathetic nerve stimulation. Adrenoceptor agonists (phenylephrine, dobutamine and salbutamol) given I.V. increased the output of 35S, and the last two drugs increased the output of 3H. The blocking effects of thymoxamine and propranolol on these… CONTINUE READING