Control of ion transport in mouse proximal and distal colon by prolactin.

@article{Puntheeranurak2007ControlOI,
  title={Control of ion transport in mouse proximal and distal colon by prolactin.},
  author={Supaporn Puntheeranurak and Rainer Schreiber and Melanie Spitzner and Jiraporn Ousingsawat and Nateetip Krishnamra and Karl Kunzelmann},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2007},
  volume={19 1-4},
  pages={77-88}
}
The lactogenic hormone prolactin (PRL) has been known to affect Ca(2+) and electrolyte transport in the intestinal epithelium. In the present study we analyzed ion transport in mouse proximal and distal colon, and acute changes induced by PRL. In the proximal colon, carbachol activated a Ca(2+) dependent Cl(-) secretion that was sensitive to DIDS and NFA. In the distal colon, both ATP and carbachol activated K(+) secretion. Ca(2+) -activated KCl transport in proximal and distal colon was… CONTINUE READING

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