Control of intestinal promoter activity of the cellular migratory regulator gene ELMO3 by CDX2 and SP1.

Abstract

An important aspect of the cellular differentiation in the intestine is the migration of epithelial cells from the crypt to the villus tip. As homeodomaine transcription factor CDX2 has been suggested to influence cell migration, we performed a genome-wide promoter analysis for CDX2 binding in the differentiated human intestinal cancer cell line Caco-2 in… (More)
DOI: 10.1002/jcb.22490

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