Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor.

@article{Mascar1998ControlOH,
  title={Control of human muscle-type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor.},
  author={Cristina Mascar{\'o} and Elisa Acosta and Jose A. Ortiz and Pedro F. Marrero and Fausto G. Hegardt and Diego Haro},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 15},
  pages={8560-3}
}
The expression of several genes involved in intra- and extracellular lipid metabolism, notably those involved in peroxisomal and mitochondrial beta-oxidation, is mediated by ligand-activated receptors, collectively referred to as peroxisome proliferator-activated receptors (PPARs). To gain more insight into the control of expression of carnitine palmitoyltransferase (CPT) genes, which are regulated by fatty acids, we have examined the transcriptional regulation of the human MCPT I gene. We have… CONTINUE READING
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