Control of granulocytes and macrophages: molecular, cellular, and clinical aspects.

@article{Metcalf1991ControlOG,
  title={Control of granulocytes and macrophages: molecular, cellular, and clinical aspects.},
  author={Don Metcalf},
  journal={Science},
  year={1991},
  volume={254 5031},
  pages={
          529-33
        }
}
The production and functional activity of two important white blood cells, the granulocytes and macrophages, are regulated mainly by a group of glycoprotein colony-stimulating factors. The colony-stimulating factors have been mass-produced with recombinant technology and are now proving of value in preventing or suppressing infections in a variety of individuals with subnormal or defective formation of blood cells. 

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