Control of gonadotropin secretion in the male during puberty: a decrease in response to steroid inhibitory feedback in the absence of an increase in steroid-independent drive in the sheep.

@article{Olster1986ControlOG,
  title={Control of gonadotropin secretion in the male during puberty: a decrease in response to steroid inhibitory feedback in the absence of an increase in steroid-independent drive in the sheep.},
  author={Deborah H. Olster and Douglas L. Foster},
  journal={Endocrinology},
  year={1986},
  volume={118 6},
  pages={
          2225-34
        }
}
The gonadostat hypothesis, i.e. that a decrease in response to the inhibitory feedback action of gonadal steroids occurs during puberty, was tested in the male lamb. Also investigated was whether a simultaneous steroid-independent rise in gonadotropin secretion could be the underlying mechanism for the reduction in steroid feedback sensitivity during puberty. Sexual maturation in intact Suffolk lambs was characterized by increases in all of the following parameters: Serum FSH and LH and LH… CONTINUE READING
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