Control of glycolysis through regulation of PFK1: old friends and recent additions.

@article{Mor2011ControlOG,
  title={Control of glycolysis through regulation of PFK1: old friends and recent additions.},
  author={Inbal Mor and Eric C. C. Cheung and Karen Heather Vousden},
  journal={Cold Spring Harbor symposia on quantitative biology},
  year={2011},
  volume={76},
  pages={211-6}
}
Regulation of glucose metabolism is a crucial aspect of cell physiology in normal and disease conditions. Many regulatory events are involved in determining the metabolic fate of glucose and the pathways into which it is directed. The first reaction that commits glucose to the glycolytic pathway is catalyzed by the enzyme phosphofructokinase-1 (PFK-1) and is tightly regulated. One of the most potent activators of PFK-1 is fructose 2,6 bisphosphate (F2,6BP) and its cellular levels are correlated… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 60 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 42 references

Similar Papers

Loading similar papers…