Control of glucuronidation during hypoxia. Limitation by UDP-glucose pyrophosphorylase.

@article{Aw1984ControlOG,
  title={Control of glucuronidation during hypoxia. Limitation by UDP-glucose pyrophosphorylase.},
  author={Tak Yee Aw and D. H. P. Jones},
  journal={The Biochemical journal},
  year={1984},
  volume={219 3},
  pages={707-12}
}
The regulation of glucuronidation during hypoxia was studied in isolated hepatocytes by analysing the dependence of acetaminophen glucuronidation rate on the intracellular concentrations of UTP, glucose 1-phosphate, UDP-glucose and UDP-glucuronic acid. The steady-state concentrations of these metabolites in cells from fed and starved rats were altered by… CONTINUE READING