Control of gene expression in bacteriophage P22 by a small antisense RNA. II. Characterization of mutants defective in repression.

@article{Wu1987ControlOG,
  title={Control of gene expression in bacteriophage P22 by a small antisense RNA. II. Characterization of mutants defective in repression.},
  author={Te-hui Wu and Sha Mei Liao and William R. McClure and Miriam M. Susskind},
  journal={Genes & development},
  year={1987},
  volume={1 2},
  pages={204-12}
}
Phage P22 produces antirepressor protein early after infection from a transcript initiated at the Pant promoter. After the first few minutes of infection, transcription from Pant is repressed by a protein encoded by the arc gene. Antirepressor is not produced late in infection, even though the antirepressor gene, ant, is transcribed from the late operon promoter Plate. We describe the isolation of P22 mutants that synthesize antirepressor from the Plate transcript. The mutations inactivate a… CONTINUE READING
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