Control of fatty acid desaturation: a mechanism conserved from bacteria to humans.

@article{Aguilar2006ControlOF,
  title={Control of fatty acid desaturation: a mechanism conserved from bacteria to humans.},
  author={Pablo S. Aguilar and Diego de Mendoza},
  journal={Molecular microbiology},
  year={2006},
  volume={62 6},
  pages={1507-14}
}
Unsaturated fatty acids (UFAs) have profound effects on the fluidity and function of biological membranes. Microorganisms, plants and animals regulate the synthesis of UFAs during changing environmental conditions as well as in response to nutrients. UFAs homeostasis in many organisms is achieved by feedback regulation of fatty acid desaturase gene transcription through signalling pathways that are governed by sensors embedded in cellular membranes. Here, we review recently discovered… CONTINUE READING

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