Experiments in vitro have suggested that IL5 is a late-acting factor in eosinophil production, and that other factors such as IL3, G-CSF and GM-CSF are required for the production of committed eosinophil progenitors. Furthermore, work in vitro indicates that in addition to IL5, both IL3 and GM-CSF are capable of stimulating eosinophil differentiation. Thus… (More)
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