Control of embryonic Xenopus morphogenesis by a Ral-GDS/Xral branch of the Ras signalling pathway.

@article{Lebreton2003ControlOE,
  title={Control of embryonic Xenopus morphogenesis by a Ral-GDS/Xral branch of the Ras signalling pathway.},
  author={St{\'e}phanie Lebreton and Laurent Boissel and Jacques Moreau},
  journal={Journal of cell science},
  year={2003},
  volume={116 Pt 22},
  pages={4651-62}
}
Ras proteins mediate biological responses through various effectors and play a key role in relaying the Fibroblast Growth Factor (FGF) mesoderm induction signal during embryogenesis of the frog, Xenopus laevis. One Ras effector pathway involves the activation of the small G protein Ral. In the present study, we have investigated the role of key components in the Ral branch of FGF and Ras signalling during early Xenopus development. Treatment of animal caps with bFGF, which converts prospective… CONTINUE READING