Control of direction of flagellar rotation in bacterial chemotaxis.

  title={Control of direction of flagellar rotation in bacterial chemotaxis.},
  author={Birgit E. Scharf and Karen A. Fahrner and Laur{\'e} Turner and Howard C. Berg},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={95 1},
The motile behavior of the bacterium Escherichia coli depends on the direction of rotation of its flagellar motors. Binding of the phosphorylated signaling molecule CheY to a motor component FliM is known to enhance clockwise rotation. It is difficult to study this interaction in vivo, because the dynamics of phosphorylation of CheY by its kinase CheA and the hydrolysis of CheY (accelerated by CheZ) are not under direct experimental control. Here, we examine instead the interaction with the… CONTINUE READING

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