Control of dihydrofolate reductase messenger ribonucleic acid production.

Abstract

We used methotrexate-resistant mouse cells in which dihydrofolate reductase levels are approximately 500 times normal to study the effect of growth stimulation on dihydrofolate reductase gene expression. As a result of growth stimulation, the relative rate of dihydrofolate reductase protein synthesis increased threefold, reaching a maximum between 25 and 30… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.