Control of cerebrovascular patterning by neural activity during postnatal development

@article{Lacoste2015ControlOC,
  title={Control of cerebrovascular patterning by neural activity during postnatal development},
  author={Baptiste Lacoste and Chenghua Gu},
  journal={Mechanisms of Development},
  year={2015},
  volume={138},
  pages={43-49}
}
The brain represents only a small portion of the body mass and yet consumes almost a quarter of the available energy, and has a limited ability to store energy. The brain is therefore highly dependent on oxygen and nutrient supply from the blood circulation, which makes it vulnerable to vascular pathologies. Key vascular determinants will ensure proper brain maturation and function: the establishment of vascular networks, the formation of the blood-brain barrier, and the regulation of blood… CONTINUE READING