Control of cell proliferation by Myc.

  title={Control of cell proliferation by Myc.},
  author={Caroline Bouchard and Peter Staller and Martin Eilers},
  journal={Trends in cell biology},
  volume={8 5},
Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis. 

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