Control of cell polarity by noncanonical Wnt signaling in C. elegans.

  title={Control of cell polarity by noncanonical Wnt signaling in C. elegans.},
  author={Michael A. Herman},
  journal={Seminars in cell & developmental biology},
  volume={13 3},
The three Caenorhabditis elegans beta-catenin each function in distinct processes: BAR-1 in canonical Wnt signaling that controls cell fates and cell migrations, HMP-2 in cell adhesion and WRM-1 in Wnt signaling pathways that function in conjunction with a mitogen-activated kinase (MAPK) pathway to control the orientations, or cell polarities, of cells that undergo asymmetric cell divisions. In addition, WRM-1 does not interact with the canonical beta-catenin binding site in POP-1/Tcf. Thus… CONTINUE READING

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