Control of calcium carbonate nucleation and crystal growth by soluble matrx of oyster shell.

@article{Wheeler1981ControlOC,
  title={Control of calcium carbonate nucleation and crystal growth by soluble matrx of oyster shell.},
  author={Alfred P Wheeler and John W George and C. A. Evans},
  journal={Science},
  year={1981},
  volume={212 4501},
  pages={1397-8}
}
A calcium-binding soluble protein extracted from oyster shell suppresses calcium carbonate nucleation and decreases the rate of crystal growth in vitro. These findings suggest that soluble matrix may regulate shell growth. 

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