Control of bioamine metabolism by 5-HT2B and alpha 1D autoreceptors through reactive oxygen species and tumor necrosis factor-alpha signaling in neuronal cells.

@article{Schneider2006ControlOB,
  title={Control of bioamine metabolism by 5-HT2B and alpha 1D autoreceptors through reactive oxygen species and tumor necrosis factor-alpha signaling in neuronal cells.},
  author={Beno{\^i}t Schneider and Math{\'e}a Pietri and Sophie Mouillet-Richard and Myriam Ermonval and Vincent Mutel and J. -F. Launay and Odile Kellermann},
  journal={Annals of the New York Academy of Sciences},
  year={2006},
  volume={1091},
  pages={123-41}
}
Homeostasis of the central nervous system relies on the proper integration of cell-signaling pathways recruited by a variety of neuronal and non-neuronal factors, with the aim of tightly controlling neurotransmitter metabolism, storage, and transport. We took advantage of the 1C11 neuroectodermal cell line, endowed with the capacity to selectively differentiate into serotonergic (1C11(5-HT)) or noradrenergic (1C11(NE)) neurons, to identify functional targets of serotonin (5-hydroxytryptamine [5… CONTINUE READING