Control of basal autophagy by calpain1 mediated cleavage of ATG5

@inproceedings{2010ControlOB,
  title={Control of basal autophagy by calpain1 mediated cleavage of ATG5},
  author={夏宏光 and 张立红 and 郭玉波 and 张涛 and 刘军力 and 金明志 and 马秀全 and Dawei Ma and 袁钧瑛},
  year={2010}
}
Autophagy functions as an important catabolic mechanism by mediating the turnover of intracellular organelles and protein complexes. Although the induction of autophagy by starvation has been extensively studied, we still understand very little about how autophagy is regulated under normal nutritional conditions. Here we describe a study using a small molecule autophagy inducer, fluspirilene, as a tool to explore the mechanism of autophagy induction in normal living cells. We confirm the… CONTINUE READING

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