Control of albumin and alpha-fetoprotein expression in rat liver and in some transplantable hepatocellular carcinomas.

@article{Sell1979ControlOA,
  title={Control of albumin and alpha-fetoprotein expression in rat liver and in some transplantable hepatocellular carcinomas.},
  author={Stewart Sell and Karen Thomas and M Michalson and J Salatrepat and James Bonner},
  journal={Biochimica et biophysica acta},
  year={1979},
  volume={564 1},
  pages={
          173-8
        }
}
Albumin and alpha-fetoprotein production by rat liver and by four selected transplantable hepatocellular carcinomas is compared to the messenger RNA present in these tissues. Albumin and alpha-fetoprotein were measured by radioimmunoassay of serum concentration, immunofluorescence, and in vitro incorporation of labeled amino acids into proteins specifically precipitated by antisera. The number of mRNA molecules per cell was calculated from the hybridization of specific cDNA probes to polysomal… CONTINUE READING
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