Control of adaptive immunity by the innate immune system

@article{Iwasaki2015ControlOA,
  title={Control of adaptive immunity by the innate immune system},
  author={Akiko Iwasaki and Ruslan Medzhitov},
  journal={Nature Immunology},
  year={2015},
  volume={16},
  pages={343-353}
}
Microbial infections are recognized by the innate immune system both to elicit immediate defense and to generate long-lasting adaptive immunity. To detect and respond to vastly different groups of pathogens, the innate immune system uses several recognition systems that rely on sensing common structural and functional features associated with different classes of microorganisms. These recognition systems determine microbial location, viability, replication and pathogenicity. Detection of these… CONTINUE READING
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