Control of acetylcholine sensitivity and synapse formation by muscle activity.

@article{Lmo1978ControlOA,
  title={Control of acetylcholine sensitivity and synapse formation by muscle activity.},
  author={Terje L\omo and Clarke R. Slater},
  journal={The Journal of physiology},
  year={1978},
  volume={275},
  pages={391-402}
}
1. The formation of ectopic junctions between the 'foreign' superficial fibular nerve and the soleus muscle of adult rats, and its relation to changes in extrajunctional sensitivity to acetylcholine (ACh), has been studied by denervating the muscle 3-6 weeks after implanting the foreign nerve. 2. The earliest signs of nerve-muscle transmission were seen 2.5-3 days after denervation, in those fibres where the extrajunctional ACh sensitivity first reached its full post-denervation level. The… CONTINUE READING