Control of acetylcholine receptors in skeletal muscle.

  title={Control of acetylcholine receptors in skeletal muscle.},
  author={Douglas M. Fambrough},
  journal={Physiological reviews},
  volume={59 1},
An ACh receptor is the molecular entity that, in its native habitat, possesses the binding sites for ACh and all the other components required to generate the ion channels mediating the ACh response. Narrower definitions of an ACh receptor (as the binding site for ACh or the polypeptide chain that is folded to form the binding site) could lead to semantic arguments about receptor structure. Experimentally, ACh receptors are defined by their total function (when electrophysiological tests are… CONTINUE READING
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