Control of RNA silencing and localization by endolysosomes.

  title={Control of RNA silencing and localization by endolysosomes.},
  author={Derrick Gibbings and Olivier Voinnet},
  journal={Trends in cell biology},
  volume={20 8},
Recent advances in the cell biology of RNA silencing have unraveled an intriguing association of post-transcriptionally regulated RNA with endolysosomal membranes in several circumstances of mRNA localization, microRNA activity and viral RNA transport and packaging. Endolysosomal membranes are a nexus of communication and transport between cells and their exterior environment for signaling receptors, pathogens and nutrients. Here, we discuss recent data that support a view that endolysosomal… CONTINUE READING