Control of Neural Development and Function in a Thermoregulatory Network by the LIM Homeobox Gene lin-11

@article{Hobert1998ControlON,
  title={Control of Neural Development and Function in a Thermoregulatory Network by the LIM Homeobox Gene lin-11},
  author={O. Hobert and T. D'Alberti and Y. Liu and G. Ruvkun},
  journal={The Journal of Neuroscience},
  year={1998},
  volume={18},
  pages={2084 - 2096}
}
We show here that the lin-11 LIM homeobox gene is expressed in nine classes of head, ventral cord, and tail neurons and functions at a late step in the development of a subset of these neurons. In a lin-11 null mutant, alllin-11-expressing neurons are generated. Several of these neurons, however, exhibit neuroanatomical as well as functional defects. In the lateral head ganglion, lin-11 functions in a neural network that regulates thermosensory behavior. It is expressed in the AIZ interneuron… Expand
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