Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene

  title={Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene},
  author={Lisa C. Ryner and Stephen F Goodwin and Diego H. Castrillon and Anuranjan Anand and Adriana Villella and Bruce S. Baker and Jeffrey C. Hall and Barbara J. Taylor and Steven A. Wasserman},
Sexual orientation and courtship behavior in Drosophila are regulated by fruitless (fru), the first gene in a branch of the sex-determination hierarchy functioning specifically in the central nervous system (CNS). The phenotypes of new fru mutants encompass nearly all aspects of male sexual behavior. Alternative splicing of fru transcripts produces sex-specific proteins belonging to the BTB-ZF family of transcriptional regulators. The sex-specific fru products are produced in only about 500 of… CONTINUE READING
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