Control of Lactate Production by Membrane Adenosine Triphosphatase Activity in Human Erythrocytes

@article{Whittam1964ControlOL,
  title={Control of Lactate Production by Membrane Adenosine Triphosphatase Activity in Human Erythrocytes},
  author={R. Whittam and M E Ager and James S. Wiley},
  journal={Nature},
  year={1964},
  volume={202},
  pages={1111-1112}
}
IT is generally believed from Schatzmann's1 work that lactate production in human erythrocytes is unaffected by ouabain and other cardiac glycosides which inhibit the active transport of sodium and potassium. The absence of a direct effect on energy production was further suggested by later studies on ion movements2,3. It has thus appeared that inhibition of active transport is unaccompanied by a change in energy production in spite of the smaller energy requirements of the cell. Active… 

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