# Control of Haemoglobin Synthesis: a Difference in the Size of the Polysomes making α and β Chains

@article{Hunt1968ControlOH,
title={Control of Haemoglobin Synthesis: a Difference in the Size of the Polysomes making $\alpha$ and $\beta$ Chains},
author={R. T. Hunt and Anthony Hunter and Alan J. Munro},
journal={Nature},
year={1968},
volume={220},
pages={481-483}
}
• Published 2 November 1968
• Biology, Computer Science
• Nature
HAEMOGLOBIN is composed of equimolar amounts of α and β chains. Although it is not essential to synthesize the same number of molecules of each chain, this was originally thought to be the case1. The finding of a pool of α chains in rabbit reticulocytes implies that either at some stage there has been excess synthesis of α chains, or that the α chains are continually produced in excess of β chains2–4. An understanding of the mechanisms which control the balance of the synthesis of the two…
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• 1974
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