Control of Drosophila embryo patterning by transcriptional co-regulators.

@article{Mannervik2014ControlOD,
  title={Control of Drosophila embryo patterning by transcriptional co-regulators.},
  author={Mattias Mannervik},
  journal={Experimental cell research},
  year={2014},
  volume={321 1},
  pages={47-57}
}
A combination of broadly expressed transcriptional activators and spatially restricted repressors are used to pattern embryos into cells of different fate. Transcriptional co-regulators are essential mediators of transcription factor function, and contribute to selective transcriptional responses in embryo development. A two step mechanism of transcriptional regulation is discussed, where remodeling of chromatin is initially required, followed by stimulation of recruitment or release of RNA… CONTINUE READING
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