Control of ACTH secretion by excitatory amino acids

@article{Jezova2005ControlOA,
  title={Control of ACTH secretion by excitatory amino acids},
  author={Daniela Jezova},
  journal={Endocrine},
  year={2005},
  volume={28},
  pages={287-293}
}
The involvement of excitatory amino acids in the control of ACTH release is well established. Activation of ionotropic glutamate receptors has a stimulatory effect on ACTH release, while the role of metabotropic receptors is not yet understood in detail. Glutamatergic regulation of ACTH release has a clear significance for the stress response and neuroendocrine functions during development. A dysregulation of the hypothalamic-pituitary-adrenocortical (HPA) axis has been reported in several… CONTINUE READING
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