Control by cytochrome c oxidase of the cellular oxidative phosphorylation system depends on the mitochondrial energy state.

@article{Piccoli2006ControlBC,
  title={Control by cytochrome c oxidase of the cellular oxidative phosphorylation system depends on the mitochondrial energy state.},
  author={Claudia Piccoli and Rosella Scrima and Domenico Boffoli and Nazzareno Capitanio},
  journal={The Biochemical journal},
  year={2006},
  volume={396 3},
  pages={573-83}
}
Recent measurements of the flux control exerted by cytochrome c oxidase on the respiratory activity in intact cells have led to a re-appraisal of its regulatory function. We have further extended this in vivo study in the framework of the Metabolic Control Analysis and evaluated the impact of the mitochondrial transmembrane electrochemical potential… CONTINUE READING