Control and statistical analysis of in vitro reporter gene assays.

  title={Control and statistical analysis of in vitro reporter gene assays.},
  author={Nick J. Plant and Michael Ogg and Michael C. Crowder and Gordon G. Gibson},
  journal={Analytical biochemistry},
  volume={278 2},
The use of in vitro gene reporter assays is becoming increasingly widespread in biology and particularly in drug metabolism, where the need for rapid screening of novel compounds is a driving factor. There is, however, little standardization of technique in the control of such assays, nor in the interpretation of results. This leads to confusion in the literature, with the possibility of a single piece of data being interpreted by several different methods, potentially giving vastly differing… CONTINUE READING

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