Control and biochemical nature of the ecdysteroidogenic pathway.

  title={Control and biochemical nature of the ecdysteroidogenic pathway.},
  author={Lawrence I. Gilbert and Robert Rybczynski and James T. Warren},
  journal={Annual review of entomology},
Molting is elicited by a critical titer of ecdysteroids that includes the principal molting hormone, 20-hydroxyecdysone (20E), and ecdysone (E), which is the precursor of 20E but also has morphogenetic roles of its own. The prothoracic glands are the predominate source of ecdysteroids, and the rate of synthesis of these polyhydroxylated sterols is critical for molting and metamorphosis. This review concerns three aspects of ecdysteroidogenesis: (a) how the brain neuropeptide prothoracicotropic… CONTINUE READING
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